Effects of neurotransmitters, gut hormones, and inflammatory mediators on mucus discharge in rat colon PASCALE PLAISANCIÉ,1,2 ALINE BARCELO,1 FREDERIC MORO,1 JEAN CLAUSTRE,1 JEAN-ALAIN CHAYVIALLE,1 AND JEAN-CLAUDE CUBER1,2
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چکیده
PASCALE PLAISANCIÉ,1,2 ALINE BARCELO,1 FREDERIC MORO,1 JEAN CLAUSTRE,1 JEAN-ALAIN CHAYVIALLE,1 AND JEAN-CLAUDE CUBER1,2 1Institut National de la Santé et de la Recherche Médicale U-45, Hôpital Edouard Herriot, 69347 Lyon Cedex 03; and 2Laboratoire d’Ecologie et de Physiologie du Système Digestif, Institut National de la Recherche Agronomique, Centre de Recherche de Jouy-en-Josas, 78352 Jouy-en-Josas, France
منابع مشابه
Effects of neurotransmitters, gut hormones, and inflammatory mediators on mucus discharge in rat colon.
The effect of potential mediators of mucus secretion was investigated in the isolated vascularly perfused rat colon by using a sandwich enzyme-linked immunosorbent assay for rat colonic mucin and by histochemical analysis. Bethanechol (100-200 μM), bombesin (100 nM), and vasoactive intestinal peptide (VIP, 100 nM) provoked a dramatic mucin discharge (maximal response at 900, 900, and 600% of co...
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